254 = 2 x 127.
254 is the maximum number of regions into which 22 lines divide a plane. It is a central polygonal number (A000124).
254 is the smallest multi-digit composite number all of whose proper divisors include the digit 2.
254 is the sum of the first 13 semiprimes (A062198).
The state of Texas has 254 counties, the most of any state of the United States.
Source: What's Special About This Number?