4220 = 2 x 5 x 211.
4220 is a number n for which the sum of the first n composite numbers is a palindrome (A053779).
4220 is the maximum number of regions the plane is divided into by 38 triangles (A077588).
4220 is the number of binary rooted trees with 39 nodes and internal path length 39 (A108643).
4220 divides 7110 - 1.
Source: What's Special About This Number?